Antidepressants and suicide risk

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Antidepressants and Suicide Risk: A Comprehensive Overview

The annual worldwide suicide rate currently averages approximately 13 per 100,000 individuals per year (0.013% per year), with higher average rates for men than for women in all but a few countries, very low rates in children, and relatively high rates in elderly men. Suicide rates vary markedly between countries, reflecting in part differences in case-identification and reporting procedures. R...

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There has been a long-standing controversy about the possibility that selective serotonin reuptake inhibitor (SSRI) antidepressants might induce suicidality in some patients. To shed light on this issue, this paper reviews available randomized controlled trials (RCTs), meta-analyses of clinical trials and epidemiological studies that have been undertaken to investigate the issue further. The or...

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Suicide, depression, and antidepressants.

Unipolar depression, one of the most important causes of disability worldwide, is characterised by depressed mood, hopelessness, helplessness, intense feelings of guilt, sadness, low self esteem, thoughts of self harm, and suicide. Up to 15% of patients with unipolar depression eventually commit suicide. Although clinical guidelines recommend treating moderate to severe depression with antidepr...

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Suicide trends and antidepressants.

The suicide rate in Sweden decreased by 25% during the 1990s. After analysing trends for the years 1978–96, I proposed that the cause might be the concurrent increased use of antidepressants, and data from Norway, Denmark, Finland, Hungary and the USA supported this hypothesis (Isacsson, 2000). However, naturalistic studies do not allow definite conclusions, which is why the importance of testi...

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Suicide trends and antidepressants

The suicide rate in Sweden decreased by 25% during the 1990s. After analysing trends for the years 1978–96, I proposed that the cause might be the concurrent increased use of antidepressants, and data from Norway, Denmark, Finland, Hungary and the USA supported this hypothesis (Isacsson, 2000). However, naturalistic studies do not allow definite conclusions, which is why the importance of testi...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2001

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.178.5.477